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The dosage in a potential human treatment would also be much lower than that used in their experiments with mice.

“In mice, TSLP-induced fat loss is dramatic (they will lose all their body fat in around 2 weeks),” Prof. Kambayashi told MNT.

“In humans, I don’t think we need to increase sebum production to that extent. Rather, enhancing sebum production by threefold or so would be sufficient to get rid of calories from one extra burger per day,” he said.

Because sebum results from the extraction of lipids from the bloodstream, he added, TSLP may improve cardiovascular health, in addition to inducing weight loss.


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